A2M & PRP Combination Therapy in Murray, Utah
Our A2M + PRP therapy delivers dual-action joint healing—blocking cartilage breakdown with A2M and regenerating tissue with PRP. A natural, long-lasting solution to pain and degeneration.
Advanced Joint Regeneration: Protect & Repair Your Joints Naturally
At American Wellness & Rehab Clinic, we are proud to offer cutting-edge regenerative therapies that go beyond symptom relief. Our A2M (Alpha-2-Macroglobulin) + PRP (Platelet-Rich Plasma) combination therapy is a powerful, natural treatment designed to both halt cartilage breakdown and stimulate tissue regeneration — addressing the two biggest challenges in joint health.
What Makes A2M + PRP So Powerful?
Understanding the Biology
Alpha-2-Macroglobulin (A2M) is a large protein in your blood plasma that acts as a biological shield against destructive enzymes called matrix metalloproteinases (MMPs) and ADAMTS enzymes. These enzymes accelerate cartilage degradation in conditions like osteoarthritis by breaking down collagen and proteoglycans—the essential building blocks of cartilage.
Platelet-Rich Plasma (PRP), on the other hand, is a concentrated source of your body’s own platelets, which release growth factors and cytokines essential for tissue repair and regeneration. PRP helps stimulate:
- New collagen formation
- Blood vessel growth (angiogenesis)
- Reduction in inflammation
- Activation of local stem cells
How They Work Together
When combined, A2M and PRP deliver a dual-action effect on joint healing:
This synergy offers long-lasting relief, not just temporary symptom masking.
Who Benefits Most from A2M + PRP?
This therapy is ideal if you:
- Have early to moderate osteoarthritis or joint degeneration
- Experience joint pain, stiffness, swelling, or loss of function
- Have cartilage thinning or meniscal fraying seen on MRI
- Have tried cortisone or hyaluronic acid (gel) injections without lasting success
- Are an athlete with overuse injuries or chronic tendonitis
Want to avoid or delay joint replacement surgery
The Procedure — What to Expect
Step 1: Comprehensive Evaluation
Our team evaluates your medical history, physical exam findings, and reviews imaging (X-ray or MRI). We may perform biomarker testing to measure enzyme levels and inflammation in the joint.
Step 2: Blood Collection & Biologic Preparation
A small sample of your blood is drawn. Using specialized centrifuges and filtration systems, we isolate and concentrate:
- The A2M protein-rich fraction
- The platelet-rich plasma (PRP) fraction
Each component is prepared under sterile conditions for maximum potency.
Step 3: Ultrasound-Guided Injection
Using ultrasound or fluoroscopic imaging, we inject the combined biologic solution directly into the joint capsule or injured tendon with precision to maximize effectiveness and minimize discomfort.
Step 4: Post-Procedure Care
You may experience mild soreness or swelling that typically resolves in a few days. We provide specific post-injection guidelines, including activity modification and physical therapy recommendations.
Recovery Timeline & Results
Most patients experience lasting relief for 9-18 months, with some benefiting for years depending on the degree of joint damage and follow-up care.
Why Choose A2M + PRP Over Traditional Treatments?
The combined approach uniquely protects your joints while stimulating true biological repair — a game-changer for long-term joint health.
Why Trust American Wellness & Rehab Clinic?
Our team specializes in holistic, evidence-based regenerative medicine and uses the latest technology for biologic preparation and ultrasound guidance. We customize treatment plans based on your unique condition and goals, integrating therapies like prolotherapy, ozone, and physical rehab for optimal joint restoration.